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Author: H. Isa

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Research Article 2026CC BYCC BY allows this article to remain publicly readable here. Any reuse must still follow the recorded source terms.Free full text

Comparative in vitro safety assessments of synthetized and plant-derived cannabidiol (CBD), and pharmacokinetics of synthetized CBD: evidence of similar toxicological profiles and accumulation upon repeated oral administration

E. T. Wong, D. Bovard, W. K. Schlage, W. Xia, H. Isa, O. Sirbu +6 more

Comparative toxicology between synthetized and plant-derived cannabidiol (CBD) remains underexplored, as most previous research has focused on a single type of CBD. This leaves uncertainties regarding whether differences in origin, purity, or extraction methods affect the safety profiles or metabolic outcomes of CBD. This study assessed the in vitro safety, in vitro hepatotoxicity, and repeated oral dose pharmacok…

Frontiers in Toxicology PubMed Central Open Access↗

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