Plant cannabinoids

Delta(9)-tetrahydrocannabinol (THC)

A diterpenoid that is 6a,7,8,10a-tetrahydro-6<em>H</em>-benzo[<em>c</em>]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy.

Definition: CHEBI:66964 · Chemical Entities of Biological Interest · release 253

2,129public articles

14registered condition areas

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Identity & provenance

Chemical identity

C21H30O2 · molecular weight 314.469

Sources: ChEBI · 253

0 referenced plant-occurrence records. They are identity candidates, not clinical evidence.

Experimental bioactivity

ChEMBL assay candidates

ChEMBL assay and bioactivity records are experimental candidates, not clinical facts, efficacy evidence or treatment recommendations. Showing 12 of 456 exact linked records.

Antiplasmodial activity against multidrug-resistant Plasmodium falciparum K1

Plasmodium falciparum · Plasmodium falciparum

IC50 = 720.0 nM · candidate, not a clinical fact

Assay CHEMBL5054967 ↗ · Target CHEMBL364 ↗ · Source document ↗

Inhibition of Beta-hematin in Plasmodium falciparum cells assessed as hemozoin formation after 32 hrs by NP40 detergent-mediated assay

Hemozoin · Plasmodium falciparum

IC50 = 11300.0 nM · candidate, not a clinical fact

Assay CHEMBL5054968 ↗ · Target CHEMBL613898 ↗ · Source document ↗

Research areas

Conditions found alongside this compound

Document links and organism occurrence are candidates, not proof of efficacy, safety or a treatment recommendation.

Linked local records

Medicines and registered studies

Links use source-reported active ingredients or study intervention names and remain candidates, not treatment claims.

Medicines with this active ingredient

DRONABINOL DRONABINOL DRONABINOL DRONABINOL DRONABINOL CAPSULE MARINOL Marinol MARINOL MARINOL CAP 10MG SATIVEX SATIVEX 2,7 MG/2,5 MG SOLUCION PARA PULVERIZACION BUCAL SYNDROS SYNDROS (DRONABINOL) SOLUTION

Registered studies

298 exact source-intervention matches.

Protocol onlyRECRUITING

Phase II, Randomized, Double-Blind, Multidose Crossover Clinical Trial to Determine the Safety and Efficacy of IHL-42X in Subjects With Obstructive Sleep Apnea

IHL-42X: 5 mg dronabinol + 125 mg acetazolamide

Protocol onlyNOT_YET_RECRUITING

Effects Of Nocturnal Dronabinol Use On Obstructive Sleep Apnea Treatment And Physiological Outcomes

Dronabinol

Protocol onlyRECRUITING

Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes

Recent research

2026

Case Report: Oral and topical chronic administration of THC-rich and CBD-rich cannabis oil as palliative care in a rescued horse with open wound, sarcoid and chronic pain.

Frontiers in Veterinary Science · Free full text

2026

Cognitive performance recovery following marijuana cessation in NCAA division I athletes.

Frontiers in Sports and Active Living · Free full text

2026

Quasi-randomization to Cannabinoid Condition in Studies of US Legal Market Cannabis: Characteristics of Accepters Versus Decliners of Condition Assignment.

Prevention Science · Free full text

2026

Navigating dose-effect complexities and challenges in cannabinoid therapy for aging-related neurobiological changes.

Frontiers in Pharmacology · Free full text