Author: hasumi akihiro

1.	CBD (Total distance) (mm)

Control　　　　 MET　　　　　 CBD0.5 　　   CBD1  　　   CBD5  　　   CBD10
Mean | 10247.72 | 11129.69 | 8490.591 | 9331.751 | 9850.076 | 8255.247
SEM | 690.4832 | 580.0485 | 1019.224 | 718.8323 | 646.8486 | 728.1092

2.	CBD (Moving distance for light or dark stimulation) (mm)

Control
         　　　　　 1^st. ON  　     1^st. OFF 　    2^nd. ON 　    2^nd. OFF 　   3^rd. ON  　   3^rd. OFF 　   4^th. ON  　　   4^th. OFF 　    5^th. ON 　　   5^th. OFF 　    6^th. ON 　    6^th. OFF  
Mean | 906.251625 | 1204.809 | 779.6034 | 1243.693 | 723.5549 | 1230.035 | 627.5537 | 1177.055 | 625.0027 | 1182.531 | 679.4737 | 1045.151
SEM | 98.8271699 | 118.6195 | 96.6812 | 130.075 | 104.4919 | 138.2268 | 68.79061 | 128.9733 | 83.89647 | 148.5726 | 94.39268 | 114.3732

MET
          　　　　　1^st. ON  　      1^st. OFF 　    2^nd. ON 　     2^nd. OFF　　    3^rd. ON 　     3^rd. OFF　　    4^th. ON 　     4^th. OFF 　    5^th. ON 　　　   5^th. OFF      6^th. ON 　　    6^th. OFF  
Mean | 810.05924 | 1288.408 | 833.6209 | 1171.83 | 647.0513 | 1244.587 | 699.6826 | 1186.368 | 700.8286 | 1126.379 | 613.2989 | 1117.028
SEM | 58.8379176 | 145.4741 | 98.53116 | 119.743 | 36.86473 | 140.1781 | 37.06749 | 130.2112 | 47.66491 | 128.4112 | 49.73988 | 106.6659

CBD0.5 (μg/mL)
        　　　　　  1^st. ON　        1^st. OFF 　　    2^nd. ON      2^nd. OFF 　　   3^rd. ON 　     3^rd. OFF　　    4^th. ON　      4^th. OFF　     5^th. ON　　　    5^th. OFF      6^th. ON　　     6^th. OFF  
Mean | 518.840857 | 929.9798 | 701.7866 | 851.264 | 476.9785 | 852.0131 | 481.5287 | 805.9281 | 463.7403 | 759.9664 | 492.015 | 768.2179
SEM | 49.0302938 | 134.2814 | 89.08546 | 136.0536 | 55.05084 | 134.5918 | 54.43235 | 141.9582 | 64.07971 | 144.6903 | 59.77358 | 139.0964

CBD1 (μg/mL)
         　　　　　 1^st. ON       1^st. OFF　　     2^nd. ON      2^nd. OFF    3^rd. ON 　　    3^rd. OFF     4^th. ON 　     4^th. OFF     5^th. ON 　　   5^th. OFF      6^th. ON　     6^th. OFF  
Mean | 716.301125 | 1025.765 | 750.2384 | 952.0431 | 643.0075 | 865.4651 | 631.8303 | 884.3618 | 441.0717 | 872.8231 | 513.5638 | 901.2386
SEM | 116.51075 | 110.8628 | 101.397 | 128.628 | 61.04078 | 142.3166 | 59.90164 | 150.4103 | 55.99405 | 101.1405 | 93.22018 | 98.01653

CBD5 (μg/mL)
         　　　 1^st. ON 　　      1^st. OFF　     2^nd. ON　     2^nd. OFF　    3^rd. ON　　     3^rd. OFF     4^th. ON 　　    4^th. OFF　     5^th. ON　　    5^th. OFF　    6^th. ON  　　    6^th. OFF 
Mean | 1073.42513 | 1239.248 | 804.3336 | 1123.914 | 540.3551 | 864.957 | 604.2035 | 917.8881 | 646.174 | 850.1795 | 646.7126 | 918.5717
SEM | 135.521068 | 116.7144 | 110.9315 | 95.36771 | 65.61747 | 49.37933 | 87.85024 | 85.38926 | 115.3323 | 63.69837 | 106.9988 | 87.8164

CBD10 (μg/mL)
          　　　　 1^st. ON　       1^st. OFF 　　   2^nd. ON 　    2^nd. OFF 　  3^rd. ON 　     3^rd. OFF 　   4^th. ON 　    4^th. OFF 　    5^th. ON  　　  5^th. OFF　     6^th. ON  　   6^th. OFF 
Mean | 904.24375 | 1033.77 | 974.596 | 779.009 | 788.5408 | 602.3382 | 716.8528 | 653.0831 | 713.4271 | 566.6301 | 563.2527 | 441.8613
SEM | 165.603468 | 122.6913 | 116.2059 | 137.1428 | 90.00869 | 117.493 | 97.18923 | 113.9404 | 100.8526 | 76.61839 | 62.83953 | 73.39462

3.	CBD (Velocity in dark) (mm/s)

Control　　　　　 MET　　　 　　CBD0.5  　　  CBD1  　　   CBD5  　　   CBD10
Mean | 1.3311743 | 1.242774 | 0.9227267 | 1.0219821 | 1.1070561 | 0.7573125
SEM | 0.140372 | 0.119227 | 0.145813 | 0.117947 | 0.078105 | 0.105431

4.	CBD (Moving Duration) (sec)

Control　　　　　 MET　　　　 CBD0.5  　　  CBD1  　　   CBD5 　　　    CBD10
Mean | 2558.073 | 2457.41 | 1727.386 | 2153.901 | 2261.333 | 1832.48

SEM | 166.69723 | 181.78967 | 240.64887 | 205.46368 | 169.14343 | 205.70294